Iressa contains Gefitinib, which is a targeted cancer medicine.
It is mainly used for certain types of lung cancer (non-small cell lung cancer – NSCLC) that have specific EGFR mutations.
Mechanism
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Some lung cancer cells have too much activity of a protein called EGFR (epidermal growth factor receptor), which makes them grow and multiply.
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Gefitinib blocks EGFR activity.
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This slows down or stops cancer cell growth and helps control the disease.
Uses
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Treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) with EGFR mutations
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Often used as first-line therapy in patients tested positive for EGFR mutations
Adverse Effects
Common side effects:
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Diarrhea
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Skin rash, dryness, itching
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Loss of appetite
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Nausea, vomiting
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Weakness, tiredness
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