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Endoxan

Endoxan

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Endoxan contains Cyclophosphamide, which is a chemotherapy medicine.
It belongs to the group called alkylating agents and is used in both cancer treatment and autoimmune diseases.

Mechanism 

  • Cyclophosphamide changes inside the body into an active form.

  • This active form attaches to DNA of cells, making cross-links.

  • As a result, cancer cells and overactive immune cells cannot divide and eventually die.

    Uses

    • Cancers:

      • Leukemia

      • Lymphoma (Hodgkin’s & Non-Hodgkin’s)

      • Breast cancer

      • Ovarian cancer

      • Multiple myeloma

    • Autoimmune diseases (when other drugs don’t work):

      • Severe rheumatoid arthritis

      • Systemic lupus erythematosus (SLE)

      • Vasculitis (inflammation of blood vessels)

    • Used before bone marrow transplant

      Adverse Effects 

      Common side effects:

      • Nausea, vomiting, loss of appetite

      • Hair loss

      • Tiredness, weakness

      • Low blood counts (risk of infections, anemia, bleeding)

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