Endoxan contains Cyclophosphamide, which is a chemotherapy medicine.
It belongs to the group called alkylating agents and is used in both cancer treatment and autoimmune diseases.
Mechanism
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Cyclophosphamide changes inside the body into an active form.
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This active form attaches to DNA of cells, making cross-links.
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As a result, cancer cells and overactive immune cells cannot divide and eventually die.
Uses
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Cancers:
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Leukemia
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Lymphoma (Hodgkin’s & Non-Hodgkin’s)
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Breast cancer
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Ovarian cancer
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Multiple myeloma
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Autoimmune diseases (when other drugs don’t work):
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Severe rheumatoid arthritis
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Systemic lupus erythematosus (SLE)
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Vasculitis (inflammation of blood vessels)
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Used before bone marrow transplant
Adverse Effects
Common side effects:
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Nausea, vomiting, loss of appetite
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Hair loss
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Tiredness, weakness
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Low blood counts (risk of infections, anemia, bleeding)
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