Entecashiv contains Entecavir, an oral antiviral medication used primarily for the treatment of chronic Hepatitis B virus (HBV) infection. Entecavir belongs to the class of nucleoside reverse transcriptase inhibitors (NRTIs) and helps suppress viral replication, reduce liver inflammation, and prevent progression to cirrhosis or liver cancer.

Mechanism of Action

• Entecavir is a guanosine nucleoside analogue that inhibits HBV DNA polymerase.

• It blocks viral DNA synthesis by acting as a chain terminator during replication.

• By inhibiting reverse transcriptase, Entecavir reduces viral load and helps the immune system control infection.

  Uses

  • Treatment of chronic Hepatitis B virus (HBV) infection in adults and adolescents.

  • Prevention of liver cirrhosis and hepatocellular carcinoma in chronic HBV patients.

  • Often used in patients with elevated liver enzymes or high viral load.

  • May be part of long-term therapy to maintain viral suppression.

    Adverse Effects

    • Headache

    • Fatigue or weakness

    • Nausea or abdominal pain

    • Dizziness