Lentris contains Lenvatinib, which is a targeted cancer medicine. It belongs to the group of drugs called tyrosine kinase inhibitors (TKIs). It is used to treat different types of cancers by stopping the growth of cancer cells and their blood supply.

Mechanism
Lenvatinib blocks proteins called tyrosine kinases that help cancer cells grow and make new blood vessels (angiogenesis). By blocking these signals, it reduces the blood supply to the tumor and slows down cancer growth.

Uses

• Thyroid cancer (when it cannot be treated with radioactive iodine)

• Liver cancer (Hepatocellular carcinoma)

• Kidney cancer (Renal cell carcinoma, usually in combination with other drugs like everolimus or pembrolizumab)

• Some other cancers in combination therapies

  Adverse Effects
  Common side effects:

  • High blood pressure

  • Fatigue, weakness

  • Loss of appetite, weight loss

  • Diarrhea, nausea, vomiting

  • Mouth sores

  • Hand-foot skin reaction, rash, hair loss