Ammobula contains Sodium Phenylbutyrate, a medication used to treat urea cycle disorders (UCDs), which are rare genetic conditions where the body cannot properly remove ammonia from the blood. By reducing elevated ammonia levels, Ammobula helps prevent neurological damage and complications associated with hyperammonemia. It is usually administered orally as a powder, granule, or capsule.

Mechanism of Action

• Sodium Phenylbutyrate is metabolized in the body to phenylacetate, which binds to glutamine, forming phenylacetylglutamine.

• This complex is excreted through the urine, effectively removing excess nitrogen from the body.

• By lowering ammonia levels, it reduces the risk of neurological damage caused by hyperammonemia.

  Uses

  • Treatment of urea cycle disorders (UCDs) in adults and children.

  • Prevention and management of hyperammonemia, which can cause confusion, vomiting, lethargy, or coma.

  • Helps maintain normal nitrogen balance in patients unable to metabolize ammonia effectively.

    Adverse Effects

    • Nausea, vomiting, or diarrhea

    • Bad taste in the mouth

    • Fatigue or headache

    • Body odor due to phenylacetate excretion