Jolltrin contains Trientine Hydrochloride, an oral chelating agent used for the treatment of Wilson’s disease, a rare genetic disorder that causes excess copper accumulation in the liver, brain, and other organs. It is especially used in patients who cannot tolerate Penicillamine. By promoting copper excretion, Jolltrin helps prevent liver damage, neurological complications, and other toxic effects caused by copper overload.

Mechanism of Action

• Trientine Hydrochloride binds free copper ions in the bloodstream, forming a stable complex.

• This copper-trientine complex is excreted primarily through the urine, effectively lowering copper levels in the body.

• By reducing copper accumulation, it prevents organ damage and complications associated with Wilson’s disease.

  Uses

  • Treatment of Wilson’s disease (copper overload).

  • For patients who are intolerant to Penicillamine.

  • Helps prevent liver damage and neurological symptoms caused by excess copper.

  • Maintenance therapy to control copper levels long-term.

    Adverse Effects

    • Nausea, vomiting, or abdominal discomfort

    • Fatigue or weakness

    • Mild rash or skin irritation

    • Joint or muscle pain