Lasinone is a diuretic medication primarily used to reduce excess fluid accumulation in the body. Its active ingredient is Spironolactone, a potassium-sparing diuretic. It works by helping the kidneys eliminate excess sodium and water while retaining potassium, which makes it useful in conditions like edema, heart failure, liver cirrhosis, and hypertension.

Mechanism of Action

• Spironolactone is an aldosterone antagonist that blocks the action of aldosterone in the distal renal tubules.

• By inhibiting aldosterone, it reduces sodium and water reabsorption while retaining potassium.

• This leads to decreased fluid overload and helps control blood pressure and swelling associated with heart, liver, or kidney conditions.

  Uses

  • Edema due to heart failure, liver cirrhosis, or kidney disorders.

  • Hypertension (high blood pressure), often in combination with other medications.

  • Primary hyperaldosteronism (excess aldosterone production).

  • Prevention of hypokalemia in patients on other diuretics.

    Adverse Effects

    • Mild gastrointestinal disturbances (nausea, vomiting, diarrhea)

    • Dizziness or headache

    • Breast tenderness or enlargement in men and women (gynecomastia)

    • Increased potassium levels (hyperkalemia)