Lasinone contains Spironolactone, a potassium-sparing diuretic. It is primarily used to remove excess fluid from the body caused by conditions like heart failure, liver cirrhosis, or kidney disorders. It is also used to treat high blood pressure and certain hormonal disorders such as primary hyperaldosteronism.
Mechanism of action:
Spironolactone works by blocking the action of aldosterone, a hormone that causes the kidneys to retain sodium and water. By inhibiting aldosterone, Lasinone promotes the excretion of sodium and water while retaining potassium, helping reduce fluid buildup, lower blood pressure, and balance electrolytes.
Uses:
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Edema (fluid retention) due to heart failure, liver cirrhosis, or kidney disease
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High blood pressure (hypertension)
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Primary hyperaldosteronism (excess aldosterone production)
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Sometimes used in hormonal acne or hirsutism in women (off-label)
Adverse effects:
Common side effects include dizziness, headache, stomach upset, nausea, and increased urination. Because it retains potassium, high potassium levels (hyperkalemia) can occur, which may be dangerous. Other possible effects include breast tenderness, menstrual irregularities, fatigue, or skin rash. Rarely, serious kidney problems or severe allergic reactions may occur.




