Mitomycin (also called Mitomycin-C) is a chemotherapy medicine.
It is an antitumor antibiotic used to treat different types of cancers.

Mechanism 

• Inside the body, Mitomycin changes into an active form.

• This active form binds to the DNA of cancer cells and cross-links it.

• As a result, the cancer cells cannot divide or grow, and they eventually die.

  Uses

  • Cancer of the stomach and pancreas

  • Cancer of the bladder (can also be given directly into the bladder)

  • Used in some other cancers (breast, lung, cervix, head & neck) in combination with other chemotherapy

  • Sometimes used in eye surgery (to prevent scarring after glaucoma surgery)

    Adverse Effects 

    Common side effects:

    • Nausea, vomiting

    • Mouth sores

    • Loss of appetite

    • Hair thinning

    • Tiredness