Neukine contains Filgrastim, which is a man-made form of a natural protein called G-CSF (Granulocyte Colony Stimulating Factor). It helps the bone marrow make more white blood cells, especially neutrophils.

Mechanism
Filgrastim works by stimulating the bone marrow to produce neutrophils (a type of white blood cell). This reduces the risk of infection in people whose white cells are low due to chemotherapy, bone marrow transplant, or other conditions.

Uses

• To prevent or treat neutropenia (low neutrophils) caused by chemotherapy

• After bone marrow or stem cell transplant

• In severe chronic neutropenia (a condition where the body cannot make enough neutrophils)

• To mobilize stem cells before stem cell collection for transplant

Adverse Effects
Common side effects:

• Bone pain (very common)

• Muscle or joint pain

• Headache

• Tiredness

• Mild fever