Nexbase-D is a combination medicine used to relieve symptoms associated with cough, cold, and respiratory tract infections. It generally contains Dextromethorphan, Chlorpheniramine maleate, and Phenylephrine, which work together to suppress cough, reduce nasal congestion, and relieve allergy symptoms like runny nose or sneezing.

Mechanism of Action:

• Dextromethorphan acts on the cough center in the brain to suppress dry cough.

• Chlorpheniramine maleate is an antihistamine that blocks histamine H1 receptors, reducing symptoms like sneezing, watery eyes, and runny nose.

• Phenylephrine is a nasal decongestant that constricts blood vessels in the nasal passages, helping to relieve congestion and sinus pressure.

  Uses:

  • Dry or allergic cough

  • Common cold, flu, and allergic rhinitis

  • Nasal congestion and throat irritation

  • Sneezing, watery eyes, and postnasal drip

    Adverse Effects:

    • Drowsiness or dizziness

    • Dry mouth or throat

    • Headache or mild nausea

    • Increased heart rate or palpitations (rare)

    • Allergic reactions like rash or itching (uncommon)