Paxlovid is an oral antiviral medication used to treat mild to moderate COVID-19 in adults and children at risk of developing severe disease. It helps reduce viral replication, lowering the risk of hospitalization or death. Paxlovid is a combination of Nirmatrelvir and Ritonavir.
Mechanism of action:
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Nirmatrelvir inhibits the SARS-CoV-2 main protease, an enzyme the virus needs to replicate.
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Ritonavir slows down the metabolism of Nirmatrelvir, increasing its effectiveness and maintaining higher levels in the body.
Together, they prevent the virus from multiplying, helping the body clear the infection faster.
Uses:
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Treatment of mild to moderate COVID-19 in patients at high risk of severe disease (e.g., older adults, people with comorbidities)
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Helps reduce hospitalization and death from COVID-19
Adverse effects:
Common side effects include altered taste (metallic or bitter), diarrhea, high blood pressure, and muscle aches. Rare but serious effects may include liver problems, severe allergic reactions, or interactions with other medications.




