Vilazine is a medicine that contains Clozapine, an antipsychotic drug used primarily to treat schizophrenia, especially in patients who do not respond well to other antipsychotics. It belongs to the class of atypical (second-generation) antipsychotics. Vilazine helps improve symptoms such as hallucinations, delusions, disorganized thinking, and mood disturbances.

Mechanism of action:
Clozapine works by blocking multiple neurotransmitter receptors in the brain, especially dopamine (D2) and serotonin (5-HT2A) receptors. This modulation helps balance brain chemical activity, reducing psychotic symptoms, improving mood, and decreasing aggressive or self-harming behavior in resistant schizophrenia.

Uses:

• Treatment of treatment-resistant schizophrenia

• Reducing risk of suicidal behavior in patients with schizophrenia or schizoaffective disorder

• Managing severe agitation or aggression in some psychiatric conditions

Adverse effects:
Common side effects include drowsiness, dizziness, increased salivation, weight gain, constipation, and blurred vision. Serious side effects can include:

• Agranulocytosis (dangerously low white blood cells), requiring regular blood monitoring

• Seizures (rare but possible)

• Heart problems such as myocarditis or irregular heartbeat

• Metabolic changes: increased blood sugar, cholesterol, or triglycerides

• Drooling, sedation, and orthostatic hypotension (drop in blood pressure on standing)